Friday, August 27, 2010

Federal school lunches -- but not breakfasts -- linked to childhood obesity, research finds

Federal School Lunches -- But Not Breakfasts -- Linked to Childhood Obesity, Research Finds


ScienceDaily (Aug. 26, 2010) — With children going back to school, parents are concerned that their youngsters are staying fit and eating right, especially those who dine in a school cafeteria.



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New research funded by the U.S. Department of Agriculture finds that children who eat school lunches that are part of the federal government's National School Lunch Program are more likely to become overweight.
The same research study found, however, that children who eat both the breakfast and lunch sponsored by the federal government are less heavy than children who don't participate in either, and than children who eat only the lunch, says economist Daniel L. Millimet at Southern Methodist University in Dallas.
Millimet authored the study with economists Rusty Tchernis, Georgia State University, and Muna S. Hussain, Kuwait University.
"The fact that federally funded school lunches contribute to the childhood obesity epidemic is disconcerting, although not altogether surprising," said Millimet, whose research expertise is the economics of children, specifically topics related to schooling and health.
The new study was published in the Summer issue of The Journal of Human Resources.
The U.S. Department of Agriculture oversees the federal lunch and breakfast programs. Through USDA the federal government reimburses schools for a portion of school lunch costs and also donates surplus agricultural food items. While USDA does require that the meals meet certain nutritional standards, schools choose the specific foods.
A la carte items outside the guidelines
Schools also can serve individual food items a la carte, which fall outside the scope of the federal guidelines and allow students to choose additional foods.
For their study, the researchers analyzed data on more than 13,500 elementary school students. Students were interviewed in kindergarten, first and third grades, and then again in later grades. "First, it is very difficult to plan healthy but inviting school lunches at a low price," Millimet said. "Second, given the tight budgets faced by many school districts, funding from the sales of a la carte lunch items receives high priority. That said, it's comforting to know that the U.S. Department of Agriculture, which oversees the federal school nutrition programs, takes the issue very seriously. The USDA sponsors not only my research, but that of others as well, to investigate the issues and possible solutions."
The USDA is partnering with First Lady Michelle Obama to fight what experts say is a childhood obesity epidemic among America's school children. The First Lady on May 18 released the results and recommendations of The White House Task Force on Childhood Obesity report, which said that more than 30 percent of American children ages 2 to 19 are overweight or obese. The report recommends serving healthier foods in schools.
Lunches may not be in compliance
Judging from the results of the study, Millimet said, the food being served in school lunches may not maintain a healthy weight in children. The food in school breakfasts appears to be healthier, however.
"Technically what is going on is that the federal government establishes nutrition guidelines for lunches and breakfasts if schools wish to receive federal funding," Millimet said. "But there's evidence that school lunches are less in compliance with these guidelines than breakfasts. The other possible issue is that these days schools try to make money from a la carte items at lunch. And it's possible that even if the school lunch is healthy, kids buying lunch are more likely to tack on extra items that are not healthy."
Nutritionists strongly advocate eating breakfast for a healthy lifestyle, Millimet said, noting that -- up to a point -- any breakfast is better than no breakfast.
The National Student Lunch Program supplies meals to about 30 million children in 100,000 public and nonprofit private schools, according to the USDA.
The School Breakfast Program gives cash assistance to more than 80,000 schools for about 10 million children.
Obesity among students takes jump
The study cites data from the National Health and Nutrition Examination Survey taken between 1971 and 1974 and again from 2003 to 2004 that found the prevalence of overweight preschool children ages 2-5 jumped from 5 percent to 13.9 percent. Among school-aged children, it jumped from 4 percent to 18.8 percent for children 6-11; and 6.1 percent to 17.4 percent for those 12-19.
Millimet is a professor and director of undergraduate studies in the SMU Department of Economics. Tchernis is an associate professor in Georgia State University's Andrew Young School of Policy Studies, and Hussain is an assistant professor in Kuwait University's Department of Economics.

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The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Southern Methodist University. The original article was written by Margaret Allen.




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Daniel L. Millimet, Rusty Tchernis and Muna Husain. School Nutrition Programs and the Incidence of Childhood Obesity. The Journal of Human Resources., 45(3):640-654 (2010) [link]





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A moment on the lips, a year on the hips

A Moment on the Lips, a Year on the Hips


ScienceDaily (Aug. 26, 2010) — A short period of excess food consumption can have long term effects on your body weight and fat storage even after the initial weight is lost. A study published in BioMed Central's open access journal Nutrition & Metabolism has found that a four-week episode of increased energy intake and decreased exercise can cause increased weight and fat mass more than two years later when compared to control individuals.



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Åsa Ernersson worked with a team of researchers from Linköping University Sweden to investigate the long term effects of a sedentary and gluttonous lifestyle. They capped the physical activity of 18 individuals and used excessive food consumption to increase their energy intake by an average of 70% for four weeks. A separate control group ate and exercised as normal.
The intervention group gained an average of 6.4 kg in body weight, which was mostly lost 6 months later. However, one year later the intervention group showed an increased fat mass compared to baseline; the differences were even greater after two and a half years. Ernersson said "The long term difference in body weight in the intervention and control groups suggests that there is an extended effect on fat mass after a short period of large food consumption and minimal exercise."
The study provides interesting new evidence to suggest that even a short period of excessive eating and a lack of exercise can potentially change an individual's physiology, causing it to be harder to lose and keep off weight. Ernersson summarised, "The change of fat mass was larger than expected when compared to the controls, it suggests that even short-term behavioural changes may have prolonged effects on health."


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The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by BioMed Central Limited, via AlphaGalileo.




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Asa Ernersson, Fredrik H Nystrom and Torbjorn Lindstrom. Long-term increase of fat mass after a four week intervention with fast food based hyper-alimentation and limitation of physical activity. Nutrition & Metabolism, (in press) [link]





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Fat distribution plays a role in weight loss success in patients at risk of diabetes

Fat Distribution Plays a Role in Weight Loss Success in Patients at Risk of Diabetes


ScienceDaily (Aug. 26, 2010) — Why is it that some people lose weight and body fat when they exercise and eat less and others don't? German researchers say MRI and magnetic resonance (MR) spectroscopy can provide the answer -- and help predict who will benefit from lifestyle changes. Results of the study are published online and will appear in the November issue of the journal Radiology.



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"You may have two individuals who weigh the same and have the same body mass index (BMI), but have very different levels of internal fat," said lead researcher and physicist Jürgen Machann, Dipl. Phys., from University Hospital Tübingen in Tübingen, Germany. "Abdominal and liver fat are the two most important factors in predicting whether a lifestyle intervention will be successful."
Machann and researchers performed MRI and MR spectroscopy on 243 individuals prior to and nine months after a lifestyle intervention. The intervention called for a weight loss of 5 percent, reducing fat intake to a maximum of 30 percent of total calories (including less than 10 percent in the form of saturated fat) and engaging in moderate physical activity such as walking at least three hours a week.
Each of the participants, which included 144 females (mean age 44.5 years) and 99 males (mean age 47.3), was considered at risk of developing type 2 diabetes as a result of obesity, measured by a body mass index (BMI) of 27 or greater or having an impaired glucose tolerance or a first-degree relative with the disease.
"Common methods, such as body impedance analysis, may determine that a body consists of 25 percent fat, but that does not tell you how the fat is distributed," Machann said. "BMI is a good measure for obesity but not necessarily a predictor for health risk, because not only the amount of fat, but also its distribution are essential. Only by looking inside the body can you establish the amount of visceral (abdominal) and liver fat."
MRI allowed researchers to differentiate fatty tissue from lean tissue throughout the body. MR spectroscopy generated additional data on the fat content of individual organs, such as the liver.
Researchers used improved insulin sensitivity to measure the success of the lifestyle intervention. Individuals with type 2 diabetes do not respond correctly to insulin, a hormone secreted by the pancreas that aids in metabolism. In pre-diabetes, cells become resistant to the action of insulin.
After nine months of participating in the lifestyle intervention, insulin sensitivity improved in 71 percent of the men and 58 percent of the women. Individuals with improved insulin sensitivity lost significant amounts of visceral fat (a mean reduction of 19 percent for women and 20 percent for men) and liver fat (a mean reduction of 35 percent for women and 44 percent for men) while reducing 3 to 5 percent of body weight.
"The participants who improved their health status as a result of diet and exercise started out with lower baseline levels of abdominal and liver fat," Machann said. "In our study, these two factors predetermined whether or not a lifestyle intervention would be successful for a particular individual."
Individuals who did not improve insulin sensitivity as a result of lifestyle changes lost much smaller amounts of visceral fat (a mean reduction of 4 percent for women and 6 percent for men). The men also lost less liver fat (a mean of 15 percent), and women gained a mean of 22 percent in liver fat.
"Our results demonstrate that with MRI and MR spectroscopy, we can determine who will benefit from dietary changes and exercise and who will need other interventions," Machann said.

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The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Radiological Society of North America, via EurekAlert!, a service of AAAS.




Journal Reference:

Machann et al. Follow-up Whole-Body Assessment of Adipose Tissue Compartments during a Lifestyle Intervention in a Large Cohort at Increased Risk for Type 2 Diabetes. Radiology, 2010; DOI: 10.1148/radiol.10092284





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Wednesday, August 25, 2010

Exercising restores sensitivity of neurons that make one feel full

Exercising Restores Sensitivity of Neurons That Make One Feel Full


ScienceDaily (Aug. 24, 2010) — There is now another good reason to exercise. Besides burning calories, exercise restores the sensitivity of neurons involved in the control of satiety (feeling full), which in turn contributes to reduced food intake and consequently weight loss. This is the conclusion of a study led by Brazilian researchers at the University of Campinas, and the findings will be published next week in the online, open access journal PLoS Biology. This disclosure may bring hope to over 40% of the population that suffers from weight problems and obesity around the world.



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The increase in obesity has become one of the most important clinical-epidemiological phenomena. Factors such as changing eating habits and a sedentary lifestyle both have a role in the pathogenesis of this disease. It is postulated that excessive consumption of fat creates failures in the signal transmitted by neurons controlling satiety in a region of the brain called the hypothalamus. These failures can lead to uncontrollable food intake and, consequently, obesity.
The group led by José Barreto C. Carvalheira demonstrated that exercising obese rodents showed signals of restored satiety in hypothalamic neurons and decreased food intake. "In obese animals, exercise increased IL-6 and IL-10 protein levels in the hypothalamus, and these molecules were crucial for increasing the sensitivity of the most important hormones, insulin and leptin, which control appetite," Carvalheira explained. Physical activity contributes to the prevention and treatment of obesity, not only by increasing energy expenditure but also by modulating the signals of satiety and reducing food intake.
Physical activity has always been considered a cornerstone in the treatment of obesity, however, only now have the effects of exercise on the control of body weight been understood. Thus, these findings, besides reinforcing the necessity for regular exercise also change the current paradigm established between physical activity and weight loss.
Funding: This study was supported by grants from Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) and Conselho Nacional de desenvolvimento científico e tecnológico (CNPq).

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The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Public Library of Science, via EurekAlert!, a service of AAAS.




Journal Reference:

Ropelle ER, Flores MB, Cintra DE, Rocha GZ, Pauli JR, et al. IL-6 and IL-10 Anti-Inflammatory Activity Links Exercise to Hypothalamic Insulin and Leptin Sensitivity through IKKb and ER Stress Inhibition. PLoS Biol, 8(8): e1000465 DOI: 10.1371/journal.pbio.1000465





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Tuesday, August 24, 2010

Cinnamon extracts may reduce risk of diabetes and heart disease, study suggests

Cinnamon Extracts May Reduce Risk of Diabetes and Heart Disease, Study Suggests


ScienceDaily (Aug. 24, 2010) — A study led by U.S. Department of Agriculture (USDA) chemist Richard Anderson suggests that a water soluble extract of cinnamon, which contains antioxidative compounds, could help reduce risk factors associated with diabetes and heart disease.



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The work is part of cooperative agreements between the Beltsville Human Nutrition Research Center (BHNRC) operated by USDA's Agricultural Research Service (ARS) at Beltsville, Md.; Integrity Nutraceuticals International of Spring Hill, Tenn., and the Joseph Fourier University in Grenoble, France. Anderson works in the Diet, Genomics and Immunology Laboratory of BHNRC. ARS is USDA's principal intramural scientific research agency.
For the study, conducted in Ohio, coauthor Tim N. Ziegenfuss, now with the Center for Applied Health Sciences based in Fairlawn, Ohio, enrolled volunteers and collected samples.
Twenty-two obese participants with impaired blood glucose values--a condition classified as "prediabetes"--volunteered for the 12-week experimental research study. Prediabetes occurs when cells are resistant to the higher-than-normal levels of insulin produced by the pancreas (in an attempt to help remove elevated glucose levels from blood).
The volunteers were divided randomly into two groups and given either a placebo or 250 milligrams (mgs) of a dried water-soluble cinnamon extract twice daily along with their usual diets. Blood was collected after an overnight fast at the beginning of the study, after six weeks, and after 12 weeks to measure the changes in blood glucose and antioxidants.
The study demonstrated that the water-soluble cinnamon extract improved a number of antioxidant variables by as much as 13 to 23 percent, and improvement in antioxidant status was correlated with decreases in fasting glucose, according to Anderson.
Only more research will tell whether the investigational study supports the idea that people who are overweight or obese could reduce oxidative stress and blood glucose by consuming cinnamon extracts that have been proven safe and effective. In the meantime, weight loss remains the primary factor in improving these numbers, according to ARS scientists.

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The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by USDA/Agricultural Research Service, via EurekAlert!, a service of AAAS. The original article was written by Rosalie Marion Bliss.




Journal Reference:

Anne-Marie Roussel, Isabelle Hininger, Rachida Benaraba, Tim N. Ziegenfuss, and Richard A. Anderson. Antioxidant Effects of a Cinnamon Extract in People with Impaired Fasting Glucose That Are Overweight or Obese. Journal of the American College of Nutrition, 2009 28: 16-21 [link]





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Decade-long trial confirms benefts of steroid withdrawal for transplant patients

Decade-Long Trial Confirms Benefts of Steroid Withdrawal for Transplant Patients


ScienceDaily (Aug. 24, 2010) — A University of Cincinnati (UC) analysis of 10 years of data from local kidney transplant patients shows that patients removed from a corticosteroid regimen shortly after surgery have better graft survival rates, better survival rates and fewer cardiovascular events than patients kept on the traditional regimen of long-term steroids.



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The analysis shows that, out of 904 patients transplanted at UC Health University Hospital and Christ Hospital, early corticosteroids withdrawal (ECSWD) patients had an 83.8 percent graft survival rate and a 91.7 percent patient survival rate, as compared to 68.6 percent graft survival and 83.6 percent patient survival for chronic corticosteroid (CCS) patients. UC's survival rates were numerically higher than national rates from the United Network for Organ Sharing (UNOS) registry.
Corticosteroids, in combination with other immunosuppressive drugs, have historically been prescribed to transplant patients to help suppress the body's immune response and allow the transplanted organ to function after surgery. But they also come with an increased risk of high blood pressure, high cholesterol, weight gain, diabetes and cardiovascular disease and events.
With development of better immunosuppressive drugs, that cardiovascular risk has come to be the chief concern for transplant patients' survival, not the loss of their new organ, explains Adele Rike Shields, PharmD, UC research assistant professor of surgery and clinical transplant pharmacist at Christ Hospital.
Four years ago, Shields says, UC researchers showed ECSWD patients had a significant reduction in cardiovascular events as opposed to CCS patients. But researchers still weren't certain whether ECSWD patients have worse long-term graft functioning due to a risk of acute rejection of the organ.
With 10 years of data, Shields says they can now answer that question definitively.
"This is the first study with enough long-term follow-up to show that we're not causing an increase in graft loss with early corticosteroid withdrawal," says Shields. "We have just as good, if not better graft results and the patients' survival is better because of their reduced cardiovascular risk."
She presented the work last week at the International Congress of The Transplantation Society in Vancouver.
Not only does the analysis show that ECSWD patients have decreased cardiovascular events, Shields says they also have a reduced risk of malignancies not associated with immunosuppressive drugs. ECSWD patients showed a 2.2 percent rate of non-PTLD cancer, one-third the rate of malignancies in CCS patients. PTLD, or post-transplant lymphoproliferative disorder, is the name given to a group of lymphomas occurring in immunosuppressed patients.
UC transplant researchers have focused on steroid withdrawal under E. Steve Woodle, MD, chief of the division of transplant surgery. Woodle calls the data from the 10-year analysis "highly statistically significant."
"To my knowledge, we are the first of any transplant program to demonstrate this magnitude of an effect," he says. "We now know without a doubt that our original hypothesis generated more than 15 years ago does indeed benefit our patients. This is the final nail in the coffin for steroid based immunosuppression for our program."

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Stress of freshman year can trigger eating disorders for some young people

Stress of Freshman Year Can Trigger Eating Disorders for Some Young People


ScienceDaily (Aug. 23, 2010) — While the start of college is a positive, momentous event for many young people, it also can be an episode that pushes some into a dangerous battle with eating disorders, says University of Alabama at Birmingham Associate Professor of Psychology Mary Boggiano, Ph.D., who fought her own battle against bulimia as a college student. Hear her story.



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Stress can trigger an eating disorder, and for the college student who is away from home for the first time, the stress of moving into a totally different environment and meeting new people can make them more susceptible to developing an eating disorder, says Boggiano. Even new positive events are processed by the brain as stressful, she says.
"A lot of students have heard about the 'freshman 15,'" says Boggiano. "To keep from gaining weight, some students engage in risky behaviors such as excessive dieting or purging food. In many cases, people learn about the risky behaviors from others students in their dorm or over the Internet, so that obsession about weight can become infectious."
Boggiano says the common signs of an eating disorder include:

A preoccupation with calculating calories, fat grams and carbohydrate grams
A need to weigh oneself more than once a day
Allowing the numbers on the scale to determine mood
Exercising, skipping meals or purging after overeating
Exercising to burn calories rather than for health or for fun
An inability to stop eating once eating begins
Eating in secret
Feeling guilty, ashamed or disgusted after overeating
Basing self-worth on looks or weight
Worrying continuously about weight and body shape
Abusing diet pills or laxatives

Eating disorders can lead to long-term health problems, and even death.
For any young people who suspect they might be developing an eating disorder, Boggiano encourages them to seek help at free campus counseling centers, through a pastor or family doctor or through programs like Overeaters Anonymous.
"Whatever you do, don't try to take care of it by yourself," says Boggiano. "It will only get worse."
Boggiano, who studies the psychobiology of eating disorders and obesity, knows this from personal experience as a young adult.
"My problems with bulimia nervosa actually began during my senior year in high school," she says. "I was a top student, salutatorian of my class. But, I became obsessed with my weight and the shape of my body. I started starving myself, but this led to binge eating and eventually vomiting after the binges, several times a day, and eventually I began abusing laxatives. When I started college, the disorder got worse."
The two most common forms of eating disorders are anorexia nervosa, when a person stops eating or eats very little to control their weight, and bulimia nervosa, when a person vomits or uses laxatives to get rid of the food they have eaten to prevent weight gain. Both types of eating disorders can eventually lead to serious health problems and even death.
Another form of eating disorder, binge eating disorders (or BED), is when an individual eats unusually large amounts of food, uncontrollably, in a short period of time until they are uncomfortable but do not purge or compensate afterward.
"This often leads to weight gain, which is upsetting to them," says Boggiano, "yet to overcome the distress, they turn to food. It's a vicious cycle." She is currently exploring brain markers of stress-induced binge-eating and the chemistry behind the action of high-fat and sugar foods to trigger relapses back to binge eating and obesity.

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